MINIMALLY INVASIVE. SIGNIFICANTLY EFFECTIVE.
A SOLUTION WITH IMPRESSIVE RESULTS.

The SPRINT PNS System has been studied extensively and ongoing clinical trials are further evaluating its impact in chronic neuropathic pain, chronic back pain, and acute post-surgical pain. SPR Therapeutics continues to support research regarding the efficacy and durability of the SPRINT PNS System across a wide spectrum of potential uses.

Clinical Data

SUMMARY OF SPRINT PNS CLINICAL OUTCOMES

SPRINT PNS CLINICAL DATA

Subjects receiving SPRINT have experienced significant pain relief. While SPRINT is indicated for use up to 30 days, subjects have experienced lasting clinical benefits after the short-term therapy.3

Significant Pain Relief (1-7, 11-16)

of patients treated with the SPRINT PNS system experienced ≥50% reduction in pain intensity or pain interference*

*not adjusted for multiplicity

Durability

of subjects continued to experience Clinically Significant Pain Relief at 12 months post-treatment3



REFERENCES

 

  1. Yu, D.T., et al., Percutaneous intramuscular neuromuscular electric stimulation for the treatment of shoulder subluxation and pain in patients with chronic hemiplegia: a pilot study. Arch Phys Med Rehabil, 2001. 82(1): p. 20-5.
  2. Yu, D.T., et al., Intramuscular neuromuscular electric stimulation for poststroke shoulder pain: a multicenter randomized clinical trial. Arch Phys Med Rehabil, 2004. 85(5): p. 695-704.
  3. Chae, J., et al., Intramuscular electrical stimulation for hemiplegic shoulder pain: a 12-month follow-up of a multiple-center, randomized clinical trial. Am J Phys Med Rehabil, 2005. 84(11): p. 832-42.
  4. Wilson, R.D., et al., Single-lead percutaneous peripheral nerve stimulation for the treatment of hemiplegic shoulder pain: a case report. Arch Phys Med Rehabil, 2011. 92(5): p. 837-40.
  5. Chae, J., et al., Single-lead percutaneous peripheral nerve stimulation for the treatment of hemiplegic shoulder pain: a case series. Pain practice: the official journal of World Institute of Pain, 2013. 13(1): p. 59-67.
  6. Wilson, R.D., et al., Peripheral nerve stimulation compared with usual care for pain relief of hemiplegic shoulder pain: a randomized controlled trial. Am J Phys Med Rehabil, 2014. 93(1): p. 17-28.
  7. Nguyen, V.Q., et al., Fully implantable peripheral nerve stimulation for the treatment of hemiplegic shoulder pain: a case report. Am J Phys Med Rehabil, 2015. 94(2): p. 146-53.
  8. Stolzenberg, D., G. Siu, and E. Cruz, Current and future interventions for glenohumeral subluxation in hemiplegia secondary to stroke. Top Stroke Rehabil, 2012. 19(5): p. 444-56.
  9. Chae, J., et al., Intramuscular electrical stimulation for shoulder pain in hemiplegia: does time from stroke onset predict treatment success? Neurorehabil Neural Repair, 2007. 21(6): p. 561-7.
  10. Renzenbrink, G.J. and I.J. MJ, Percutaneous neuromuscular electrical stimulation (P-NMES) for treating shoulder pain in chronic hemiplegia. Effects on shoulder pain and quality of life. Clin Rehabil, 2004. 18(4): p. 359-65.
  11. Chae, J., D. Yu, and M. Walker, Percutaneous, intramuscular neuromuscular electrical stimulation for the treatment of shoulder subluxation and pain in chronic hemiplegia: a case report. Am J Phys Med Rehabil, 2001. 80(4): p. 296-301.
  12. Rauck, R.L., et al., Treatment of post-amputation pain with peripheral nerve stimulation. Neuromodulation: journal of the International Neuromodulation Society, 2014. 17(2): p. 188-97.
  13. Rauck, R.L., et al., Peripheral nerve stimulation for the treatment of post-amputation pain–a case report. Pain practice: the official journal of World Institute of Pain, 2012. 12(8): p. 649-55.
  14. Kapural L, Gilmore CA, Chae J, et al. Percutaneous Peripheral Nerve Stimulation for the Treatment of Chronic Low Back Pain: Two Clinical Case Reports of Sustained Pain Relief. Pain Pract. 2017. doi: 10.1111/papr.12571
  15. Ilfeld, B.M. and S.A. Grant, Ultrasound-Guided Percutaneous Peripheral Nerve Stimulation for Postoperative Analgesia: Could Neurostimulation Replace Continuous Peripheral Nerve Blocks? Reg Anesth Pain Med, 2016.
  16. Ilfeld, B. M., et al., Infection Rates of Electrical Leads Used for Percutaneous Neurostimulation of the Peripheral Nervous System.  (2016) Pain Pract.